A significant shift in the US Food and Drug Administration (FDA) occurred when Peter Marks, a leading vaccine official, was reportedly forced to resign after confronting the new secretary of Health and Human Services (HHS), Robert F Kennedy Jr. Marks submitted his resignation letter after being presented with a choice between resigning or being terminated. In his letter, which has been shared with various media outlets, Mr. Marks expressed his belief that the HHS secretary was more interested in perpetuating misinformation rather than upholding the principles of truth and transparency in public health.

Marks played a pivotal role in the development of Covid-19 vaccines during the Trump administration and has been a respected figure within the FDA since 2012, being appointed as the Director of the Center for Biologics Evaluation and Research in 2016. The HHS's response to Marks’ resignation indicated a clear stance on the need to align with the new leadership's vision of promoting scientific integrity and transparency, suggesting that Marks' unwillingness to comply with these changes left him no place in the agency.

In his resignation letter, Marks voiced grave concerns over the ongoing measles outbreak in Texas, noting that recent incidents illustrate the dangers of undermining established scientific consensus. The outbreak has resulted in two fatalities and over 500 reported cases nationally, with a substantial number occurring in Texas alone.

Secretary Kennedy, a notable vaccine skeptic, has recently outlined plans to significantly restructure the HHS, announcing a workforce reduction of approximately 10,000 employees, including critical positions within the FDA and the CDC. This restructuring has raised alarms among public health advocates regarding the potential ramifications for vaccine advocacy and public health initiatives in the United States.